Short-, Medium-, and Long-Term Cardiometabolic Outcomes in First-Episode Psychosis: A Systematic Review and Meta-analysis.
OUTPUT STRUCTURE:
Quick Take: Proactive cardiometabolic screening and management are critically important from the onset of first-episode psychosis.
š” Clinical Impact
- Early, integrated cardiometabolic screening can mitigate significant, progressive health risks for a vulnerable patient population.
- Demands a shift towards routine cardiometabolic assessment and intervention as part of standard first-episode psychosis care, regardless of duration since diagnosis.
š Evidence Breakdown
- Evidence Grade: 8/10
- Analysis: A robust systematic review and meta-analysis consolidates strong evidence, demonstrating a sustained, elevated risk for cardiometabolic complications across short, medium, and long terms in patients with first-episode psychosis.
š©ŗ Practice Recommendation
Integrate immediate and ongoing cardiometabolic screening and management strategies into all first-episode psychosis care plans. This is a definitive clinical imperative.